Knowledge Base
A collection of scientific publications, practical articles, and reflections from my journey across neuroscience, biotech, AI, health education, and personal growth.
Filter by type or topic to explore what interests you.
Pharmacology Research & Perspectives, 2025
A forward-looking perspective on how ethnopharmacology can train next-generation researchers to bridge traditional knowledge with modern technology.
Future Oncology, 2023
A translational outlook on glycoproteomics-based liquid biopsy and its potential role in colorectal cancer clinical management across Southeast Asia.
Molecular Therapy, 2017
Developed engineered exosomes as delivery vehicles for therapeutic proteins — bridging cell biology with translational medicine.
Nature Communications, 2017
Showed how cellular energy status controls inflammation via the transcriptional co-repressor CtBP — linking metabolism to immune function.
Methods, 2015
Demonstrated that the tumour suppressor PTEN is secreted via exosomes — a discovery with implications for intercellular signalling and cancer biology.
Journal of Molecular Cell Biology, 2015
Identified how Ndfip1 controls PTEN localisation to regulate cell growth — a key mechanism linking protein trafficking to tumour suppression.
Journal of Biological Chemistry, 2015
Expanded the Ndfip1 story into DNA damage repair, showing its role in ubiquitinating and trafficking BRAT1 — connecting protein trafficking to genome stability.
Traffic, 2014
Showed that Rab5 and Ndfip1 cooperate to regulate PTEN ubiquitination and nuclear transport — foundational work in cellular signalling and trafficking.
Cerebral Cortex, 2014
Demonstrated that Ndfip1 is essential for proper brain development, specifically for the growth of dendrites and spines in cortical neurons.
Experimental Neurology, 2014
Resolved a key question in neurobiology by showing that PTEN nuclear translocation after brain injury promotes neuronal survival, not cell death.
Neuroscience Letters, 2013
Characterised Ndfip1 expression patterns in the developing brain, supporting its role in ubiquitination pathways that shape cortical development.
Science Signaling, 2012
First demonstration that PTEN is packaged into exosomes and remains enzymatically active in recipient cells — a landmark finding in intercellular communication.
Journal of Cell Biology, 2012
Demonstrated in vivo that Ndfip1-controlled PTEN nuclear import protects neurons after stroke — a translational finding with therapeutic potential.
The Edge Malaysia, November 2024
Exploring how ethnopharmacology can empower the next generation of researchers by integrating traditional knowledge with modern drug discovery.
The Edge Malaysia, February 2024
A playful yet poignant reflection on why science lacks the cultural glamour of entertainment, and how we might infuse passion into marketing scientific progress.
The Edge Malaysia, June 2023
A follow-up deep dive into the structural factors behind PhD unemployment in Malaysia — from MyBrain15 to the middle-income trap — with four strategic recommendations.
The Malaysian Reserve, May 2023
An analysis of rising PhD unemployment in Malaysia, exploring systemic causes and offering actionable recommendations for government, industry, and graduates.
The Edge Malaysia, July 2026
A reflection on the promise and hidden costs of AI work: the productive breakthroughs, late-night troubleshooting, and need for more sustainable ways to build with intelligent tools.
The Edge Malaysia, May 2023
A call for Malaysia to embrace AI with an open heart — exploring parallels between Gutenberg's printing press and large language models, with policy recommendations for equitable adoption.
The Star, August 2026
An evidence-informed perspective on dementia prevention, locally tailored brain-health strategies, and Malaysia's need to turn new guidance into action.
The Edge Malaysia, August 2026
A reflection on the emerging philanthropy potential of AI wealth and the questions Malaysia should ask as the technology sector matures.
BernamaBiz, April 2025
A Bernama feature on genetic discrimination in Malaysia that mentions Dr Low Ley Hian’s work at Genetix and the role of genetic testing.
Cancer Research Malaysia, March 2026
A Cancer Research Malaysia profile of Dr Low Ley Hian and the lean business-development team translating cancer research into sustainable real-world impact.
Buletin Mutiara, August 2024
A Buletin Mutiara report on the Malaysian Breast Cancer Summit 2024 that identifies Dr Low Ley Hian as head of Genetix business development.
New Straits Times, April 2023
A letter on using artificial intelligence responsibly as large language models begin reshaping healthcare, education, finance, and everyday life.
Whether through life science strategy, AI-enabled workflows, or education, I help translate insight into practical progress.
